Nidus Prime

Nidus Meta Arbi

Nidus Prime

Max strength for maximum goodness Updated Sept 5, 2026

Nidus Prime Build

Nidus Prime

Creds to Sharky (Sapphire#146) ask him about this build

Nidus Prime Build

Nidus Prime

Nidus General Use to Level Cap

Nidus Prime

Persistence vs no persistence Persistence Nidus is fairly free once you get enough Mutation stacks, especially so now after his rework. If you're using the Abundant Mutation augment, you can get up to 500 Mutation stacks, which gives you a ridiculous amount of HP and you will truly be extremely difficult to take down. However, I like using Nidus without Persistence because it's more fun, in my opinion. These 2 builds are in context to solo level cap Void Cascade. Tharros Lethality's Crit Damage debuff is also applied to Thrax ghosts, so it makes it significantly easier to take them down when they're at max level. If you're in a squad, I highly recommend using Persistence. Solo level cap Void Cascade with no Persistence pre-rework video: link Empty Arcane slot is the flex slot Full Ability Breakdown Passive: This is also called Nidus's "Death Gate" mechanic. Because Nidus has no shields and cannot gain shields, his Death Gate basically serves this purpose. Nidus's max Mutation stack is 200 (with Passive Augment it's 500, but Death Gate has a 30 second cooldown). The following grants Nidus 1/5 of a Mutation stack: Each enemy hit with his 1 Each enemy hit with his 4 Maggot explosion Enemies killed while held in his 2 (from any source) have a 50% chance (scaling with Strength up to 100%) of giving 1/5 of a Mutation stack. What Mutation stacks do for Nidus and his abilities: 15 Mutation stacks is the Death Gate threshold, which gives 5 seconds of invulnerability upon activation at the cost of 15 Mutation stacks. Nidus 4 requires 3 Mutation stack to cast Nidus 1 and 4 damage scales with Mutation stacks Nidus's appearance changes with more Mutation stacks (from 3 - 10 only) 1st Ability: This is Nidus's energy regen ability, which also grants Mutation stacks when it hits enemies. Lower Efficiency means this ability regens more energy per enemy hit. If Nidus is linked to a squad member or enemy with his 3, his 1 will also be cast from what he's linked to in the direction you casted your 1. Gains 1/5 Mutation stack per enemy hit Holding down your 1 will allow you to aim with an indicator on the ground. 1st Augment: Teeming Virulence gives % multiplicative primary Crit Chance (so it's additive with Crit Chance mods). 2nd Ability: This is Nidus's grouping ability. This ability grabs enemies (within Line of Sight) and ragdolls them. Enemies killed while grabbed by his 2 have a 50% chance to grant 1/5 Mutation stack, and this % chance scales up to 100% at 200% Strength. 3rd Ability: This is Nidus's Buff/Damage Redirection ability. When linked to a squad member: Link grants Nidus and linked ally Ability Strength and a Universal Weapon Bonus. The Universal Weapon Bonus is a separate damage multiplier that is applied to anything considered a weapon, including some Warframe abilities. This damage multiplier is multiplicative to total base damage and is multiplicative to other damage multipliers like Roar. It does not affect the additive damage bonus from Condition Overload. Both buffs scale with Ability Strength. Has a link range of 40m. When linked to an enemy: Link grants Nidus up to 90% Damage Redirection and total status immunity. The enemy linked to Nidus is incapacitated and does not take damage until the link is stopped. 3rd Augment: This augment mod gives Nidus and a linked Ally 4% HP max health per Mutation stack. The 4% HP scales with Strength, so you can get up to 11-12% HP per Mutation stack. 4th Ability: This is Nidus's AoE Mutation stacking machine. Costs 3 Mutation stacks to cast. If you do not subsume over this ability, pairing this with your 2 and 1 allows you to gain numerous Mutation stacks. Each Maggot explosion grants 1/5 Mutation stack per enemy per explosion. Infestation field grants Nidus and allies within it health regen per second. Allied units include eidolon lures, hostages, defense objects, etc. 4th Augment: Insatiable mod changes the base % chance to gain Mutation stacks from your 4 to now scale with Ability Strength, granting the possibility to gain multiple Mutation stacks.

Nidus Prime Build

Nidus Prime

Nidus Prime Build

Nidus Prime